Cargando…

Epigenetic Changes in Mitochondrial Superoxide Dismutase in the Retina and the Development of Diabetic Retinopathy

OBJECTIVE: To investigate the role of epigenetic regulation of the manganese superoxide dismutase gene (sod2) in the development of diabetic retinopathy and the metabolic memory phenomenon associated with its continued progression after hyperglycemia is terminated. RESEARCH DESIGN AND METHODS: Strep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Qing, Kowluru, Renu A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064104/ https://www.ncbi.nlm.nih.gov/pubmed/21357467 http://dx.doi.org/10.2337/db10-0133

Ejemplares similares

Abrogation of MMP-9 Gene Protects Against the Development of Retinopathy in Diabetic Mice by Preventing Mitochondrial Damage
por: Kowluru, Renu A., et al.
Publicado: (2011)

Role of Glyceraldehyde 3-Phosphate Dehydrogenase in the Development and Progression of Diabetic Retinopathy
por: Kanwar, Mamta, et al.
Publicado: (2009)

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats
por: Akude, Eli, et al.
Publicado: (2011)

Regulation of Matrix Metalloproteinase-9 by Epigenetic Modifications and the Development of Diabetic Retinopathy
por: Zhong, Qing, et al.
Publicado: (2013)

Mitochondrial Stability in Diabetic Retinopathy: Lessons Learned From Epigenetics
por: Kowluru, Renu A.
Publicado: (2019)

Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy
por: Mohammad, Ghulam, et al.
Publicado: (2019)

Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy
por: Ni, Rui, et al.
Publicado: (2016)

Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2020)

Heritability of Proliferative Diabetic Retinopathy
por: Hietala, Kustaa, et al.
Publicado: (2008)

Long Noncoding RNAs and Mitochondrial Homeostasis in the Development of Diabetic Retinopathy
por: Kowluru, Renu A.
Publicado: (2022)

Epigenetic Modifications and Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2013)

Epigenetics and Regulation of Oxidative Stress in Diabetic Retinopathy
por: Duraisamy, Arul J., et al.
Publicado: (2018)

Marrow-Derived Cells Regulate the Development of Early Diabetic Retinopathy and Tactile Allodynia in Mice
por: Li, Guangyuan, et al.
Publicado: (2012)

Montelukast Prevents Early Diabetic Retinopathy in Mice
por: Bapputty, Reena, et al.
Publicado: (2019)

Matrix Metalloproteinase-2 in the Development of Diabetic Retinopathy and Mitochondrial Dysfunction
por: Mohammad, Ghulam, et al.
Publicado: (2010)

Per2 Mutation Recapitulates the Vascular Phenotype of Diabetes in the Retina and Bone Marrow
por: Bhatwadekar, Ashay D., et al.
Publicado: (2013)

Cross Talks between Oxidative Stress, Inflammation and Epigenetics in Diabetic Retinopathy
por: Kowluru, Renu A.
Publicado: (2023)

Increased Expression and Activity of 12-Lipoxygenase in Oxygen-Induced Ischemic Retinopathy and Proliferative Diabetic Retinopathy: Implications in Retinal Neovascularization
por: Al-Shabrawey, Mohamed, et al.
Publicado: (2011)

Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy
por: Thounaojam, Menaka C., et al.
Publicado: (2019)

Novel Detection and Restorative Levodopa Treatment for Preclinical Diabetic Retinopathy
por: Motz, Cara T., et al.
Publicado: (2020)

Glycated Hemoglobin and the Risk of Kidney Disease and Retinopathy in Adults With and Without Diabetes
por: Selvin, Elizabeth, et al.
Publicado: (2011)

Therapeutic Effects of PPARα Agonists on Diabetic Retinopathy in Type 1 Diabetes Models
por: Chen, Ying, et al.
Publicado: (2013)

Mitochondrial Dynamics in the Metabolic Memory of Diabetic Retinopathy
por: Mohammad, Ghulam, et al.
Publicado: (2022)

Angiotensin II Type 1 Receptor Signaling Contributes to Synaptophysin Degradation and Neuronal Dysfunction in the Diabetic Retina
por: Kurihara, Toshihide, et al.
Publicado: (2008)

Epigenetic Changes in Bone Marrow Progenitor Cells Influence the Inflammatory Phenotype and Alter Wound Healing in Type 2 Diabetes
por: Gallagher, Katherine A., et al.
Publicado: (2015)

Liver X Receptor Modulates Diabetic Retinopathy Outcome in a Mouse Model of Streptozotocin-Induced Diabetes
por: Hazra, Sugata, et al.
Publicado: (2012)

Pericyte Migration: A Novel Mechanism of Pericyte Loss in Experimental Diabetic Retinopathy
por: Pfister, Frederick, et al.
Publicado: (2008)

Therapeutic Potential of a Monoclonal Antibody Blocking the Wnt Pathway in Diabetic Retinopathy
por: Lee, Kyungwon, et al.
Publicado: (2012)

Protein Kinase C-δ Mediates Neuronal Apoptosis in the Retinas of Diabetic Rats via the Akt Signaling Pathway
por: Kim, Young-Hee, et al.
Publicado: (2008)

Hyperhexosemia-Induced Retinal Vascular Pathology in a Novel Primate Model of Diabetic Retinopathy
por: Chronopoulos, Argyrios, et al.
Publicado: (2015)

Plasma Exosomes Contribute to Microvascular Damage in Diabetic Retinopathy by Activating the Classical Complement Pathway
por: Huang, Chao, et al.
Publicado: (2018)

Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARα
por: Chen, Qian, et al.
Publicado: (2017)

Intervention With an Erythropoietin-Derived Peptide Protects Against Neuroglial and Vascular Degeneration During Diabetic Retinopathy
por: McVicar, Carmel M., et al.
Publicado: (2011)

CD40 in Retinal Müller Cells Induces P2X(7)-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy
por: Portillo, Jose-Andres C., et al.
Publicado: (2017)

Effect of Intensive Diabetes Therapy on the Progression of Diabetic Retinopathy in Patients With Type 1 Diabetes: 18 Years of Follow-up in the DCCT/EDIC
Publicado: (2015)

New Diabetes Diagnostic Threshold of Hemoglobin A(1c) and the 3-Year Incidence of Retinopathy
por: Tsugawa, Yusuke, et al.
Publicado: (2012)

Differentiating Microaneurysm Pathophysiology in Diabetic Retinopathy Through Objective Analysis of Capillary Nonperfusion, Inflammation, and Pericytes
por: An, Dong, et al.
Publicado: (2022)

Diabetic Stroke Severity: Epigenetic Remodeling and Neuronal, Glial, and Vascular Dysfunction
por: Kalani, Anuradha, et al.
Publicado: (2015)

Mitochondrial Fragmentation in a High Homocysteine Environment in Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2022)

Transgenic Control of Mitochondrial Fission Induces Mitochondrial Uncoupling and Relieves Diabetic Oxidative Stress
por: Galloway, Chad A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_cqtevdofc8reeg3akf6v4djq6h