Deoxyribonucleotide Metabolism in Cycling and Resting Human Fibroblasts with a Missense Mutation in p53R2, a Subunit of Ribonucleotide Reductase

Ribonucleotide reduction provides deoxynucleotides for nuclear and mitochondrial (mt) DNA replication and DNA repair. In cycling mammalian cells the reaction is catalyzed by two proteins, R1 and R2. A third protein, p53R2, with the same function as R2, occurs in minute amounts. In quiescent cells, p...

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Detalles Bibliográficos
Autores principales: Pontarin, Giovanna, Ferraro, Paola, Rampazzo, Chiara, Kollberg, Gittan, Holme, Elisabeth, Reichard, Peter, Bianchi, Vera
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064167/
https://www.ncbi.nlm.nih.gov/pubmed/21297166
http://dx.doi.org/10.1074/jbc.M110.202283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064167/
https://www.ncbi.nlm.nih.gov/pubmed/21297166
http://dx.doi.org/10.1074/jbc.M110.202283

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