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Dopamine-Induced Apoptosis of Lactotropes Is Mediated by the Short Isoform of D2 Receptor

Dopamine, through D2 receptor (D2R), is the major regulator of lactotrope function in the anterior pituitary gland. Both D2R isoforms, long (D2L) and short (D2S), are expressed in lactotropes. Although both isoforms can transduce dopamine signal, they differ in the mechanism that leads to cell respo...

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Detalles Bibliográficos
Autores principales: Radl, Daniela Betiana, Ferraris, Jimena, Boti, Valeria, Seilicovich, Adriana, Sarkar, Dipak Kumar, Pisera, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064585/
https://www.ncbi.nlm.nih.gov/pubmed/21464994
http://dx.doi.org/10.1371/journal.pone.0018097

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