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HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells

Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase which promotes cell proliferation and survival, is abnormally overexpressed in numerous tumors of epithelial origin, including colorectal cancer (CRC). EGFR monoclonal antibodies have been shown to increase the median survival and a...

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Detalles Bibliográficos
Autores principales:	Chou, Chia-Wei, Wu, Ming-Shiang, Huang, Wei-Chien, Chen, Ching-Chow
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064594/ https://www.ncbi.nlm.nih.gov/pubmed/21464950 http://dx.doi.org/10.1371/journal.pone.0018087

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