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β(2)-Adrenergic Ion-Channel Coupled Receptors as Conformational Motion Detectors
Ion Channel-Coupled Receptors (ICCRs) are artificial proteins comprised of a G protein-coupled receptor and a fused ion channel, engineered to couple channel gating to ligand binding. These novel biological objects have potential use in drug screening and functional characterization, in addition to...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064670/ https://www.ncbi.nlm.nih.gov/pubmed/21464970 http://dx.doi.org/10.1371/journal.pone.0018226 |