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Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis

Nucleolar Essential Protein 1 (Nep1) is required for small subunit (SSU) ribosomal RNA (rRNA) maturation and is mutated in Bowen–Conradi Syndrome. Although yeast (Saccharomyces cerevisiae) Nep1 interacts with a consensus sequence found in three regions of SSU rRNA, the molecular details of the inter...

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Detalles Bibliográficos
Autores principales:	Thomas, Seth R., Keller, Christopher A., Szyk, Agnieszka, Cannon, Joe R., LaRonde-LeBlanc, Nicole A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064781/ https://www.ncbi.nlm.nih.gov/pubmed/21087996 http://dx.doi.org/10.1093/nar/gkq1131

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