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7SK small nuclear RNA directly affects HMGA1 function in transcription regulation
Non-coding (nc) RNAs are increasingly recognized to play important regulatory roles in eukaryotic gene expression. The highly abundant and essential 7SK ncRNA has been shown to negatively regulate RNA Polymerase II transcription by inactivating the positive transcription elongation factor b (P-TEFb)...
Autores principales: | Eilebrecht, Sebastian, Brysbaert, Guillaume, Wegert, Thomas, Urlaub, Henning, Benecke, Bernd-Joachim, Benecke, Arndt |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064786/ https://www.ncbi.nlm.nih.gov/pubmed/21087998 http://dx.doi.org/10.1093/nar/gkq1153 |
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