Efficient and versatile manipulation of the peripheral CD4(+) T-cell compartment by antigen targeting to DNGR-1/CLEC9A

DC NK lectin group receptor-1 (DNGR-1, also known as CLEC9A) is a C-type lectin receptor expressed by mouse CD8α(+) DC and by their putative equivalents in human. DNGR-1 senses necrosis and regulates CD8(+) T-cell cross-priming to dead-cell-associated antigens. In addition, DNGR-1 is a target for se...

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Detalles Bibliográficos
Autores principales: Joffre, Olivier P, Sancho, David, Zelenay, Santiago, Keller, Anna M, Reis e Sousa, Caetano
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064981/
https://www.ncbi.nlm.nih.gov/pubmed/20333625
http://dx.doi.org/10.1002/eji.201040419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064981/
https://www.ncbi.nlm.nih.gov/pubmed/20333625
http://dx.doi.org/10.1002/eji.201040419

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