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Efficient and versatile manipulation of the peripheral CD4(+) T-cell compartment by antigen targeting to DNGR-1/CLEC9A
DC NK lectin group receptor-1 (DNGR-1, also known as CLEC9A) is a C-type lectin receptor expressed by mouse CD8α(+) DC and by their putative equivalents in human. DNGR-1 senses necrosis and regulates CD8(+) T-cell cross-priming to dead-cell-associated antigens. In addition, DNGR-1 is a target for se...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
WILEY-VCH Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064981/ https://www.ncbi.nlm.nih.gov/pubmed/20333625 http://dx.doi.org/10.1002/eji.201040419 |