DSC3 expression is regulated by p53, and methylation of DSC3 DNA is a prognostic marker in human colorectal cancer

BACKGROUND: Desmocollin 3 (DSC3), a member of the cadherin superfamily and integral component of desmosomes, is involved in carcinogenesis. However, the role of DSC3 in colorectal cancer (CRC) has not yet been established. METHODS: Desmocollin 3 expression in CRC cell lines was analysed by RT–PCR an...

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Detalles Bibliográficos
Autores principales: Cui, T, Chen, Y, Yang, L, Knösel, T, Zöller, K, Huber, O, Petersen, I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065270/
https://www.ncbi.nlm.nih.gov/pubmed/21364582
http://dx.doi.org/10.1038/bjc.2011.28

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