Morphological predictors of BRCA1 germline mutations in young women with breast cancer

BACKGROUND: Knowing a young woman with newly diagnosed breast cancer has a germline BRCA1 mutation informs her clinical management and that of her relatives. We sought an optimal strategy for identifying carriers using family history, breast cancer morphology and hormone receptor status data. METHOD...

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Detalles Bibliográficos
Autores principales: Southey, M C, Ramus, S J, Dowty, J G, Smith, L D, Tesoriero, A A, Wong, E E M, Dite, G S, Jenkins, M A, Byrnes, G B, Winship, I, Phillips, K-A, Giles, G G, Hopper, J L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065278/
https://www.ncbi.nlm.nih.gov/pubmed/21343941
http://dx.doi.org/10.1038/bjc.2011.41