Cargando…

Morphological predictors of BRCA1 germline mutations in young women with breast cancer

BACKGROUND: Knowing a young woman with newly diagnosed breast cancer has a germline BRCA1 mutation informs her clinical management and that of her relatives. We sought an optimal strategy for identifying carriers using family history, breast cancer morphology and hormone receptor status data. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Southey, M C, Ramus, S J, Dowty, J G, Smith, L D, Tesoriero, A A, Wong, E E M, Dite, G S, Jenkins, M A, Byrnes, G B, Winship, I, Phillips, K-A, Giles, G G, Hopper, J L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065278/ https://www.ncbi.nlm.nih.gov/pubmed/21343941 http://dx.doi.org/10.1038/bjc.2011.41

Ejemplares similares

Tumour morphology predicts PALB2 germline mutation status
por: Teo, Z L, et al.
Publicado: (2013)

BRCA1 mutations and other sequence variants in a population-based sample of Australian women with breast cancer
por: Southey, M C, et al.
Publicado: (1999)

Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations
por: Dite, G S, et al.
Publicado: (2010)

Prospective validation of the breast cancer risk prediction model BOADICEA and a batch-mode version BOADICEACentre
por: MacInnis, R J, et al.
Publicado: (2013)

Risk factors for breast cancer in young women by oestrogen receptor and progesterone receptor status
por: McCredie, M R E, et al.
Publicado: (2003)

Tumour morphology of early-onset breast cancers predicts breast cancer risk for first-degree relatives: the Australian Breast Cancer Family Registry
por: Dite, Gillian S, et al.
Publicado: (2012)

Population-based estimates of age-specific cumulative risk of breast cancer for pathogenic variants in ATM
por: Renault, Anne-Laure, et al.
Publicado: (2022)

Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry
por: Smith, Letitia D, et al.
Publicado: (2011)

Population-Based Estimate of Prostate Cancer Risk for Carriers of the HOXB13 Missense Mutation G84E
por: MacInnis, Robert J., et al.
Publicado: (2013)

Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2
por: Ligtenberg, M J L, et al.
Publicado: (1999)

A PALB2 mutation associated with high risk of breast cancer
por: Southey, Melissa C, et al.
Publicado: (2010)

Comparing the frequency of common genetic variants and haplotypes between carriers and non-carriers of BRCA1 and BRCA2 deleterious mutations in Australian women diagnosed with breast cancer before 40 years of age
por: Turkovic, Lidija, et al.
Publicado: (2010)

Validation study of risk prediction models for female relatives of Australian women with breast cancer
por: MacInnis, R, et al.
Publicado: (2012)

Cytomegalovirus, Epstein–Barr virus and risk of breast cancer before age 40 years: a case–control study
por: Richardson, A K, et al.
Publicado: (2004)

Familial Aspects of Mammographic Density Measures Associated with Breast Cancer Risk
por: Nguyen, Tuong L., et al.
Publicado: (2022)

Genetic Aspects of Mammographic Density Measures Associated with Breast Cancer Risk
por: Li, Shuai, et al.
Publicado: (2022)

Cirrus: An Automated Mammography-Based Measure of Breast Cancer Risk Based on Textural Features
por: Schmidt, Daniel F, et al.
Publicado: (2018)

Variance of age-specific log incidence decomposition (VALID): a unifying model of measured and unmeasured genetic and non-genetic risks
por: Hopper, John L, et al.
Publicado: (2023)

Risk of colorectal cancer for carriers of a germline mutation in POLE or POLD1
por: Buchanan, Daniel D., et al.
Publicado: (2017)

A multi-center study to evaluate the impact of germline BRCA1 and BRCA2 mutations on ovarian cancer survival
por: Bolton, KL, et al.
Publicado: (2012)

Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes
por: Win, A K, et al.
Publicado: (2011)

The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers
por: Spurdle, Amanda B, et al.
Publicado: (2005)

Anti-Müllerian hormone serum concentrations of women with germline BRCA1 or BRCA2 mutations
por: Phillips, Kelly-Anne, et al.
Publicado: (2016)

Going Beyond Conventional Mammographic Density to Discover Novel Mammogram-Based Predictors of Breast Cancer Risk
por: Hopper, John L, et al.
Publicado: (2020)

Reproductive risk factors and oestrogen/progesterone receptor-negative breast cancer in the Breast Cancer Family Registry
por: Work, M E, et al.
Publicado: (2014)

Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families
por: Teo, Zhi L, et al.
Publicado: (2013)

Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry
por: Walker, Logan C., et al.
Publicado: (2017)

Population-Based Estimates of the Age-Specific Cumulative Risk of Breast Cancer for Pathogenic Variants in CHEK2: Findings from the Australian Breast Cancer Family Registry
por: Nguyen-Dumont, Tú, et al.
Publicado: (2021)

Mammographic density defined by higher than conventional brightness thresholds better predicts breast cancer risk
por: Nguyen, Tuong L, et al.
Publicado: (2017)

High frequency of pathogenic non-founder germline mutations in BRCA1 and BRCA2 in families with breast and ovarian cancer in a founder population
por: Maksimenko, J., et al.
Publicado: (2018)

Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis
por: Edwards, S M, et al.
Publicado: (2010)

Endometrial Cancer Risk in Women With Germline BRCA1 or BRCA2 Mutations: Multicenter Cohort Study
por: de Jonge, Marthe M, et al.
Publicado: (2021)

Adequacy of risk-reducing gynaecologic surgery in BRCA1 or BRCA2 mutation carriers and other women at high risk of pelvic serous cancer
por: Kiely, B. E., et al.
Publicado: (2011)

Chemotherapy toxicity and activity in patients with pancreatic ductal adenocarcinoma and germline BRCA1-2 pathogenic variants (gBRCA1-2pv): a multicenter survey
por: Orsi, G., et al.
Publicado: (2021)

Rare germline mutations in the BRCA2 gene are associated with early-onset prostate cancer
por: Agalliu, I, et al.
Publicado: (2007)

The Impact of a Comprehensive Risk Prediction Model for Colorectal Cancer on a Population Screening Program
por: Saya, Sibel, et al.
Publicado: (2020)

Age-dependent penetrance of different germline mutations in the BRCA1 gene
por: Al-Mulla, F, et al.
Publicado: (2009)

Contribution of BRCA1 germline mutation in patients with sporadic breast cancer
por: Malik, Fraz A, et al.
Publicado: (2008)

BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers
por: Maxwell, Kara N., et al.
Publicado: (2017)

Prostate screening uptake in Australian BRCA1 and BRCA2 carriers
por: McKinley, Joanne M, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_952p87vl7vmaurlf0jvr4v81f3