Potentiation of apoptosis by histone deacetylase inhibitors and doxorubicin combination: cytoplasmic cathepsin B as a mediator of apoptosis in multiple myeloma

BACKGROUND: Although inhibitors of histone deacetylase inhibitors (HDACis) in combination with genotoxins potentiate apoptosis, the role of proteases other than caspases in this process remained elusive. Therefore, we examined the potentiation of apoptosis and related mechanisms of HDACis and doxoru...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheriyath, V, Kuhns, M A, Kalaycio, M E, Borden, E C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065279/
https://www.ncbi.nlm.nih.gov/pubmed/21364585
http://dx.doi.org/10.1038/bjc.2011.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065279/
https://www.ncbi.nlm.nih.gov/pubmed/21364585
http://dx.doi.org/10.1038/bjc.2011.42

Ejemplares similares