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Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells

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BACKGROUND: The development of a successful immunotherapy is hampered by an ineffective T-cell repertoire against tumour antigens and the inability of the patient's immune system to overcome tolerance-inducing mechanisms. Here, we test the specific recognition and lytical potential of allo-rest...

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Detalles Bibliográficos
Autores principales:	Thiel, U, Pirson, S, Müller-Spahn, C, Conrad, H, Busch, D H, Bernhard, H, Burdach, S, Richter, G H S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065285/ https://www.ncbi.nlm.nih.gov/pubmed/21407224 http://dx.doi.org/10.1038/bjc.2011.54

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