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Advanced Computational Biology Methods Identify Molecular Switches for Malignancy in an EGF Mouse Model of Liver Cancer

The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant transformation are largely unknown. To better understand EGFs' transforming capacity whole genome scans were applied to a transgenic mouse model of liver cancer and subjected to advanced methods...

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Detalles Bibliográficos
Autores principales: Stegmaier, Philip, Voss, Nico, Meier, Tatiana, Kel, Alexander, Wingender, Edgar, Borlak, Juergen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065454/
https://www.ncbi.nlm.nih.gov/pubmed/21464922
http://dx.doi.org/10.1371/journal.pone.0017738