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Advanced Computational Biology Methods Identify Molecular Switches for Malignancy in an EGF Mouse Model of Liver Cancer
The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant transformation are largely unknown. To better understand EGFs' transforming capacity whole genome scans were applied to a transgenic mouse model of liver cancer and subjected to advanced methods...
Autores principales: | Stegmaier, Philip, Voss, Nico, Meier, Tatiana, Kel, Alexander, Wingender, Edgar, Borlak, Juergen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065454/ https://www.ncbi.nlm.nih.gov/pubmed/21464922 http://dx.doi.org/10.1371/journal.pone.0017738 |
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