A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain

Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal ‘tail’. Although poorly understood, NS1 multimerization may autoregulate its actions. While RBD dimerization seems functionally con...

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Detalles Bibliográficos
Autores principales: Kerry, Philip S., Ayllon, Juan, Taylor, Margaret A., Hass, Claudia, Lewis, Andrew, García-Sastre, Adolfo, Randall, Richard E., Hale, Benjamin G., Russell, Rupert J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065461/
https://www.ncbi.nlm.nih.gov/pubmed/21464929
http://dx.doi.org/10.1371/journal.pone.0017946

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