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In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

Protein misfolding cyclic amplification (PMCA) recapitulates the prion protein (PrP) conversion process under cell-free conditions. PMCA was initially established with brain material and then with further simplified constituents such as partially purified and recombinant PrP. However, availability o...

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Detalles Bibliográficos
Autores principales:	Mays, Charles E., Yeom, Jihyun, Kang, Hae-Eun, Bian, Jifeng, Khaychuk, Vadim, Kim, Younghwan, Bartz, Jason C., Telling, Glenn C., Ryou, Chongsuk
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065467/ https://www.ncbi.nlm.nih.gov/pubmed/21464935 http://dx.doi.org/10.1371/journal.pone.0018047

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