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LPA5 Is Abundantly Expressed by Human Mast Cells and Important for Lysophosphatidic Acid Induced MIP-1β Release

BACKGROUND: Lysophosphatidic acid (LPA) is a bioactive lipid inducing proliferation, differentiation as well as cytokine release by mast cells through G-protein coupled receptors. Recently GPR92/LPA5 was identified as an LPA receptor highly expressed by cells of the immune system, which prompted us...

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Detalles Bibliográficos
Autores principales: Lundequist, Anders, Boyce, Joshua A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065470/
https://www.ncbi.nlm.nih.gov/pubmed/21464938
http://dx.doi.org/10.1371/journal.pone.0018192