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ROCK Inhibitor Y-27632 Suppresses Dissociation-Induced Apoptosis of Murine Prostate Stem/Progenitor Cells and Increases Their Cloning Efficiency

Activation of the RhoA/ROCK signaling pathway has been shown to contribute to dissociation-induced apoptosis of embryonic and neural stem cells. We previously demonstrated that approximately 1 out of 40 Lin(−)Sca-1(+)CD49f(high) (LSC) prostate basal epithelial cells possess the capacities of stem ce...

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Detalles Bibliográficos
Autores principales:	Zhang, Li, Valdez, Joseph M., Zhang, Boyu, Wei, Lei, Chang, Jiang, Xin, Li
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065488/ https://www.ncbi.nlm.nih.gov/pubmed/21464902 http://dx.doi.org/10.1371/journal.pone.0018271

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