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Advanced retinoblastoma treatment: targeting hypoxia by inhibition of the mammalian target of rapamycin (mTOR) in LH(BETA)T(AG) retinal tumors

PURPOSE: The purpose of this study is to analyze the dose response of the mammalian target of rapamycin (mTOR) inhibitor, rapamycin, on tumor burden and hypoxia, and study the treatment effect on vasculature in LH(BETA)T(AG) retinal tumors. METHODS: This study was approved by the Institutional Anima...

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Detalles Bibliográficos
Autores principales:	Piña, Y, Decatur, C, Murray, TG, Houston, SK, Gologorsky, D, Cavalcante, M, Cavalcante, L, Hernandez, E, Celdran, M, Feuer, W, Lampidis, T
Formato:	Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065577/ https://www.ncbi.nlm.nih.gov/pubmed/21468343 http://dx.doi.org/10.2147/OPTH.S16172

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