Promyelocytic sarcoma of the sternum: a case report and review of the literature

This study reports a case of promyelocytic sarcoma that developed as a solitary sternal mass without any clinical evidence of acute promyelocytic leukemia. The case presented the diagnostic difficulties common to all aleukemic granulocytic sarcomas, and diagnosis was made possible by local identific...

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Detalles Bibliográficos
Autores principales: Thomas, Xavier, Chelghoum, Youcef
Formato: Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065629/
https://www.ncbi.nlm.nih.gov/pubmed/21461306
http://dx.doi.org/10.5045/kjh.2011.46.1.52
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author Thomas, Xavier
Chelghoum, Youcef
author_facet Thomas, Xavier
Chelghoum, Youcef
author_sort Thomas, Xavier
collection PubMed
description This study reports a case of promyelocytic sarcoma that developed as a solitary sternal mass without any clinical evidence of acute promyelocytic leukemia. The case presented the diagnostic difficulties common to all aleukemic granulocytic sarcomas, and diagnosis was made possible by local identification of the PML/RARα fusion gene by fluorescent in situ hybridization. The patient was treated by surgery followed by chemotherapy plus all-trans retinoic acid therapy and local radiotherapy.
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spelling pubmed-30656292011-03-31 Promyelocytic sarcoma of the sternum: a case report and review of the literature Thomas, Xavier Chelghoum, Youcef Korean J Hematol Case Report This study reports a case of promyelocytic sarcoma that developed as a solitary sternal mass without any clinical evidence of acute promyelocytic leukemia. The case presented the diagnostic difficulties common to all aleukemic granulocytic sarcomas, and diagnosis was made possible by local identification of the PML/RARα fusion gene by fluorescent in situ hybridization. The patient was treated by surgery followed by chemotherapy plus all-trans retinoic acid therapy and local radiotherapy. Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2011-03 2011-03-15 /pmc/articles/PMC3065629/ /pubmed/21461306 http://dx.doi.org/10.5045/kjh.2011.46.1.52 Text en © 2011 Korean Society of Hematology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Thomas, Xavier
Chelghoum, Youcef
Promyelocytic sarcoma of the sternum: a case report and review of the literature
title Promyelocytic sarcoma of the sternum: a case report and review of the literature
title_full Promyelocytic sarcoma of the sternum: a case report and review of the literature
title_fullStr Promyelocytic sarcoma of the sternum: a case report and review of the literature
title_full_unstemmed Promyelocytic sarcoma of the sternum: a case report and review of the literature
title_short Promyelocytic sarcoma of the sternum: a case report and review of the literature
title_sort promyelocytic sarcoma of the sternum: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065629/
https://www.ncbi.nlm.nih.gov/pubmed/21461306
http://dx.doi.org/10.5045/kjh.2011.46.1.52
work_keys_str_mv AT thomasxavier promyelocyticsarcomaofthesternumacasereportandreviewoftheliterature
AT chelghoumyoucef promyelocyticsarcomaofthesternumacasereportandreviewoftheliterature

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