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ncIDP-assign: a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins

Summary: We describe here the ncIDP-assign extension for the popular NMR assignment program SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of connected resonances...

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Detalles Bibliográficos
Autores principales: Tamiola, Kamil, Mulder, Frans A. A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065690/
https://www.ncbi.nlm.nih.gov/pubmed/21372082
http://dx.doi.org/10.1093/bioinformatics/btr054
Descripción
Sumario:Summary: We describe here the ncIDP-assign extension for the popular NMR assignment program SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of connected resonances to the correct position in the sequence by making use of IDP random coil chemical shifts. Availability: The ncIDP-assign extension is available at http://www.protein-nmr.org/. Contact: k.tamiola@rug.nl; f.a.a.mulder@rug.nl; support@protein-nmr.org