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Acetaminophen-cysteine adducts during therapeutic dosing and following overdose
BACKGROUND: Acetaminophen-cysteine adducts (APAP-CYS) are a specific biomarker of acetaminophen exposure. APAP-CYS concentrations have been described in the setting of acute overdose, and a concentration >1.1 nmol/ml has been suggested as a marker of hepatic injury from acetaminophen overdose in...
Autores principales: | Heard, Kennon J, Green, Jody L, James, Laura P, Judge, Bryan S, Zolot, Liza, Rhyee, Sean, Dart, Richard C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066114/ https://www.ncbi.nlm.nih.gov/pubmed/21401949 http://dx.doi.org/10.1186/1471-230X-11-20 |
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