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Induction of Cyclooxygenase-2 Expression by Hepatitis B Virus Depends on Demethylation-associated Recruitment of Transcription Factors to the Promoter

BACKGROUND: The hepatitis B virus (HBV) is a major etiological factor of inflammation and damage to the liver resulting in hepatocellular carcinoma. Transcription factors play important roles in the disordered gene expression and liver injury caused by HBV. However, the molecular mechanisms behind t...

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Detalles Bibliográficos
Autores principales: Yue, Xin, Yang, Fang, Yang, Yongbo, Mu, Yongxin, Sun, Wei, Li, Wei, Xu, Dongping, Wu, Jianguo, Zhu, Ying
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066118/
https://www.ncbi.nlm.nih.gov/pubmed/21401943
http://dx.doi.org/10.1186/1743-422X-8-118