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Biological and immunological characterization of recombinant Yellow Fever 17D Viruses expressing a Trypanosoma cruzi Amastigote Surface Protein-2 CD8(+ )T cell epitope at two distinct regions of the genome
BACKGROUND: The attenuated Yellow fever (YF) 17D vaccine virus is one of the safest and most effective viral vaccines administered to humans, in which it elicits a polyvalent immune response. Herein, we used the YF 17D backbone to express a Trypanosoma cruzi CD8(+ )T cell epitope from the Amastigote...
Autores principales: | Nogueira, Raquel T, Nogueira, Alanderson R, Pereira, Mirian CS, Rodrigues, Maurício M, Galler, Ricardo, Bonaldo, Myrna C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066119/ https://www.ncbi.nlm.nih.gov/pubmed/21418577 http://dx.doi.org/10.1186/1743-422X-8-127 |
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