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Molecular Architecture of the Human Mediator–RNA Polymerase II–TFIIF Assembly

The macromolecular assembly required to initiate transcription of protein-coding genes, known as the Pre-Initiation Complex (PIC), consists of multiple protein complexes and is approximately 3.5 MDa in size. At the heart of this assembly is the Mediator complex, which helps regulate PIC activity and...

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Detalles Bibliográficos
Autores principales:	Bernecky, Carrie, Grob, Patricia, Ebmeier, Christopher C., Nogales, Eva, Taatjes, Dylan J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066130/ https://www.ncbi.nlm.nih.gov/pubmed/21468301 http://dx.doi.org/10.1371/journal.pbio.1000603

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