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Opposing Roles for Membrane Bound and Soluble Fas Ligand in Glaucoma-Associated Retinal Ganglion Cell Death

Glaucoma, the most frequent optic neuropathy, is a leading cause of blindness worldwide. Death of retinal ganglion cells (RGCs) occurs in all forms of glaucoma and accounts for the loss of vision, however the molecular mechanisms that cause RGC loss remain unclear. The pro-apoptotic molecule, Fas li...

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Detalles Bibliográficos
Autores principales: Gregory, Meredith S., Hackett, Caroline G., Abernathy, Emma F., Lee, Karen S., Saff, Rebecca R., Hohlbaum, Andreas M., Moody, Krishna-sulayman L., Hobson, Maura W., Jones, Alexander, Kolovou, Paraskevi, Karray, Saoussen, Giani, Andrea, John, Simon W. M., Chen, Dong Feng, Marshak-Rothstein, Ann, Ksander, Bruce R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066205/
https://www.ncbi.nlm.nih.gov/pubmed/21479271
http://dx.doi.org/10.1371/journal.pone.0017659