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RNAi-Based Screening Identifies Kinases Interfering with Dioxin-Mediated Up-Regulation of CYP1A1 Activity

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a transcription factor activated by several environmental pollutants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and involved in carcinogenesis and various physiological processes, including immune response and endocrine functions. Characte...

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Detalles Bibliográficos
Autores principales:	Gilot, David, Le Meur, Nolwenn, Giudicelli, Fanny, Le Vée, Marc, Lagadic-Gossmann, Dominique, Théret, Nathalie, Fardel, Olivier
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066211/ https://www.ncbi.nlm.nih.gov/pubmed/21479225 http://dx.doi.org/10.1371/journal.pone.0018261

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