BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications

Pleomorphic xanthoastrocytoma (PXA) is low-grade glial neoplasm principally affecting children and young adults. Approximately 40% of PXA are reported to recur within 10 years of primary resection. Upon recurrence, patients receive radiation therapy and conventional chemotherapeutics designed for hi...

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Detalles Bibliográficos
Autores principales: Dias-Santagata, Dora, Lam, Quynh, Vernovsky, Kathy, Vena, Natalie, Lennerz, Jochen K., Borger, Darrell R., Batchelor, Tracy T., Ligon, Keith L., Iafrate, A. John, Ligon, Azra H., Louis, David N., Santagata, Sandro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066220/
https://www.ncbi.nlm.nih.gov/pubmed/21479234
http://dx.doi.org/10.1371/journal.pone.0017948

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