Importin α7 Is Essential for Zygotic Genome Activation and Early Mouse Development

Importin α is involved in the nuclear import of proteins. It also contributes to spindle assembly and nuclear membrane formation, however, the underlying mechanisms are poorly understood. Here, we studied the function of importin α7 by gene targeting in mice and show that it is essential for early e...

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Detalles Bibliográficos
Autores principales: Rother, Franziska, Shmidt, Tatiana, Popova, Elena, Krivokharchenko, Alexander, Hügel, Stefanie, Vilianovich, Larissa, Ridders, Michael, Tenner, Katja, Alenina, Natalia, Köhler, Matthias, Hartmann, Enno, Bader, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066239/
https://www.ncbi.nlm.nih.gov/pubmed/21479251
http://dx.doi.org/10.1371/journal.pone.0018310

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