Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

Plasmalemmal neurotransmitter transporters (NTTs) regulate the level of neurotransmitters, such as dopamine (DA) and glutamate, following their release at brain synapses. Stimuli including protein kinase C (PKC) activation can lead to the internalization of some NTTs and a reduction in neurotransmit...

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Detalles Bibliográficos
Autores principales: Cremona, M. Laura, Matthies, Heinrich J.G., Pau, Kelvin, Bowton, Erica, Speed, Nicole, Lute, Brandon J., Anderson, Monique, Sen, Namita, Robertson, Sabrina D., Vaughan, Roxanne A., Rothman, James E., Galli, Aurelio, Javitch, Jonathan A., Yamamoto, Ai
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066276/
https://www.ncbi.nlm.nih.gov/pubmed/21399631
http://dx.doi.org/10.1038/nn.2781

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