In vitro functional effects of XPC gene rare variants from bladder cancer patients

The XPC gene is involved in repair of bulky DNA adducts formed by carcinogenic metabolites and oxidative DNA damage, both known bladder cancer risk factors. Single nucleotide polymorphisms (SNPs) in XPC have been associated with increased bladder cancer risk. Recently, rarer genetic variants have be...

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Detalles Bibliográficos
Autores principales: Qiao, Boling, Ansari, Abdul-Haq, Scott, Gina B., Sak, Sei C., Chambers, Philip A., Elliott, Faye, Teo, Mark T.W., Bentley, Johanne, Churchman, Michael, Hall, Janet, Taylor, Claire F., Bishop, Timothy D., Knowles, Margaret A., Kiltie, Anne E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Molecular Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066418/
https://www.ncbi.nlm.nih.gov/pubmed/21273643
http://dx.doi.org/10.1093/carcin/bgr005

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