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Epstein–Barr virus LMP2A imposes sensitivity to apoptosis
In cell lines, the Epstein–Barr virus (EBV)-encoded protein latent membrane protein 2A (LMP2A) protects B-cells from apoptosis by blocking B-cell receptor (BCR) signalling. However, EBV-infected B-cells in vivo are extremely different from cell lines. This study used a murine transgenic model in whi...
Autores principales: | Swanson-Mungerson, Michelle, Bultema, Rebecca, Longnecker, Richard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066549/ https://www.ncbi.nlm.nih.gov/pubmed/20484564 http://dx.doi.org/10.1099/vir.0.021444-0 |
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