The Reorientation of T-Cell Polarity and Inhibition of Immunological Synapse Formation by CD46 Involves Its Recruitment to Lipid Rafts

Many infectious agents utilize CD46 for infection of human cells, and therapeutic applications of CD46-binding viruses are now being explored. Besides mediating internalization to enable infection, binding to CD46 can directly alter immune function. In particular, ligation of CD46 by antibodies or b...

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Detalles Bibliográficos
Autores principales: Ludford-Menting, Mandy J., Crimeen-Irwin, Blessing, Oliaro, Jane, Pasam, Anupama, Williamson, David, Pedersen, Natalie, Guillaumot, Patricia, Christansen, Dale, Manie, Serge, Gaus, Katharina, Russell, Sarah M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3067059/
https://www.ncbi.nlm.nih.gov/pubmed/21490803
http://dx.doi.org/10.1155/2011/521863

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