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The Alternative Splice Variant of Protein Tyrosine Kinase 6 Negatively Regulates Growth and Enhances PTK6-Mediated Inhibition of β-Catenin

Protein tyrosine kinase 6 (PTK6), also called breast tumor kinase (BRK), is expressed in epithelial cells of various tissues including the prostate. Previously it was shown that PTK6 is localized to epithelial cell nuclei in normal prostate, but becomes cytoplasmic in human prostate tumors. PTK6 is...

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Detalles Bibliográficos
Autores principales: Brauer, Patrick M., Zheng, Yu, Evans, Mark D., Dominguez-Brauer, Carmen, Peehl, Donna M., Tyner, Angela L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068133/
https://www.ncbi.nlm.nih.gov/pubmed/21479203
http://dx.doi.org/10.1371/journal.pone.0014789