Cargando…
The Alternative Splice Variant of Protein Tyrosine Kinase 6 Negatively Regulates Growth and Enhances PTK6-Mediated Inhibition of β-Catenin
Protein tyrosine kinase 6 (PTK6), also called breast tumor kinase (BRK), is expressed in epithelial cells of various tissues including the prostate. Previously it was shown that PTK6 is localized to epithelial cell nuclei in normal prostate, but becomes cytoplasmic in human prostate tumors. PTK6 is...
Autores principales: | Brauer, Patrick M., Zheng, Yu, Evans, Mark D., Dominguez-Brauer, Carmen, Peehl, Donna M., Tyner, Angela L. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068133/ https://www.ncbi.nlm.nih.gov/pubmed/21479203 http://dx.doi.org/10.1371/journal.pone.0014789 |
Ejemplares similares
-
PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
por: Wozniak, Darren J., et al.
Publicado: (2017) -
Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients
por: Aubele, M, et al.
Publicado: (2008) -
Expression of protein tyrosine kinase 6 (PTK6) in nonsmall cell lung cancer and their clinical and prognostic significance
por: Zhao, Chao, et al.
Publicado: (2013) -
Protein tyrosine kinase 6 regulates activation of SRC kinase
por: Alwanian, Wanian M., et al.
Publicado: (2022) -
Prognostic impact of PTK6 expression in triple negative breast cancer
por: Chen, Yuexia, et al.
Publicado: (2023)