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Anti-Diarrheal Mechanism of the Traditional Remedy Uzara via Reduction of Active Chloride Secretion

BACKGROUND AND PURPOSE: The root extract of the African Uzara plant is used in traditional medicine as anti-diarrheal drug. It is known to act via inhibition of intestinal motility, but malabsorptive or antisecretory mechanisms are unknown yet. EXPERIMENTAL APPROACH: HT-29/B6 cells and human colonic...

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Detalles Bibliográficos
Autores principales: Schulzke, Jörg D., Andres, Susanne, Amasheh, Maren, Fromm, Anja, Günzel, Dorothee
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068135/
https://www.ncbi.nlm.nih.gov/pubmed/21479205
http://dx.doi.org/10.1371/journal.pone.0018107