Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease

BACKGROUND: Antibodies (Abs) produced during HIV-1 infection rarely neutralize a broad range of viral isolates; only eight broadly-neutralizing (bNt) monoclonal (M)Abs have been isolated. Yet, to be effective, an HIV-1 vaccine may have to elicit the essential features of these MAbs. The V genes of a...

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Detalles Bibliográficos
Autores principales: Breden, Felix, Lepik, Christa, Longo, Nancy S., Montero, Marinieve, Lipsky, Peter E., Scott, Jamie K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068138/
https://www.ncbi.nlm.nih.gov/pubmed/21479208
http://dx.doi.org/10.1371/journal.pone.0016857

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