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p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury

The side effects of cancer therapy on normal tissues limit the success of therapy. Generation of reactive oxygen species (ROS) has been implicated for numerous chemotherapeutic agents including doxorubicin (DOX), a potent cancer chemotherapeutic drug. The production of ROS by DOX has been linked to...

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Detalles Bibliográficos
Autores principales:	Velez, Joyce M., Miriyala, Sumitra, Nithipongvanitch, Ramaneeya, Noel, Teresa, Plabplueng, Chotiros D., Oberley, Terry, Jungsuwadee, Paiboon, Van Remmen, Holly, Vore, Mary, St. Clair, Daret K.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068154/ https://www.ncbi.nlm.nih.gov/pubmed/21479164 http://dx.doi.org/10.1371/journal.pone.0018005

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