Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms

[Image: see text] The enantioselectivity of a chiral catalyst can be determined from its racemic form by mass spectrometric screening of a nonequal mixture of two mass-labeled quasienantiomeric substrates. The presented method opens up new possibilities for evaluating catalyst structures that are no...

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Autores principales: Ebner, Christian, Müller, Constanze A., Markert, Christian, Pfaltz, Andreas
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068606/
https://www.ncbi.nlm.nih.gov/pubmed/21401128
http://dx.doi.org/10.1021/ja111700e
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author Ebner, Christian
Müller, Constanze A.
Markert, Christian
Pfaltz, Andreas
author_facet Ebner, Christian
Müller, Constanze A.
Markert, Christian
Pfaltz, Andreas
author_sort Ebner, Christian
collection PubMed
description [Image: see text] The enantioselectivity of a chiral catalyst can be determined from its racemic form by mass spectrometric screening of a nonequal mixture of two mass-labeled quasienantiomeric substrates. The presented method opens up new possibilities for evaluating catalyst structures that are not readily available in enantiomerically pure form.
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spelling pubmed-30686062011-03-31 Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms Ebner, Christian Müller, Constanze A. Markert, Christian Pfaltz, Andreas J Am Chem Soc [Image: see text] The enantioselectivity of a chiral catalyst can be determined from its racemic form by mass spectrometric screening of a nonequal mixture of two mass-labeled quasienantiomeric substrates. The presented method opens up new possibilities for evaluating catalyst structures that are not readily available in enantiomerically pure form. American Chemical Society 2011-03-14 2011-04-06 /pmc/articles/PMC3068606/ /pubmed/21401128 http://dx.doi.org/10.1021/ja111700e Text en Copyright © 2011 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org.
spellingShingle Ebner, Christian
Müller, Constanze A.
Markert, Christian
Pfaltz, Andreas
Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms
title Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms
title_full Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms
title_fullStr Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms
title_full_unstemmed Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms
title_short Determining the Enantioselectivity of Chiral Catalysts by Mass Spectrometric Screening of Their Racemic Forms
title_sort determining the enantioselectivity of chiral catalysts by mass spectrometric screening of their racemic forms
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068606/
https://www.ncbi.nlm.nih.gov/pubmed/21401128
http://dx.doi.org/10.1021/ja111700e
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