Characterization of the transcriptional regulator Rv3124 of Mycobacterium tuberculosis identifies it as a positive regulator of molybdopterin biosynthesis and defines the functional consequences of a non-synonymous SNP in the Mycobacterium bovis BCG orthologue

A number of single-nucleotide polymorphisms (SNPs) have been identified in the genome of Mycobacterium bovis BCG Pasteur compared with the sequenced strain M. bovis 2122/97. The functional consequences of many of these mutations remain to be described; however, mutations in genes encoding regulators...

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Detalles Bibliográficos
Autores principales: Mendoza Lopez, Pablo, Golby, Paul, Wooff, Esen, Garcia, Javier Nunez, Garcia Pelayo, M. Carmen, Conlon, Kevin, Gema Camacho, Ana, Hewinson, R. Glyn, Polaina, Julio, Suárez García, Antonio, Gordon, Stephen V.
Formato: Texto
Lenguaje:English
Publicado: Microbiology Society 2010
Materias:
Genes and Genomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068679/
https://www.ncbi.nlm.nih.gov/pubmed/20378651
http://dx.doi.org/10.1099/mic.0.037200-0

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