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Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestis

Synthesis of the siderophore yersiniabactin (Ybt) proceeds by a mixed nonribosomal peptide synthetase/polyketide synthase mechanism. Transcription of ybt genes encoding biosynthetic and transport functions is repressed under excess iron conditions by Fur, but is also activated by Ybt via the transcr...

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Detalles Bibliográficos
Autores principales:	Miller, M. Clarke, Fetherston, Jacqueline D., Pickett, Carol L., Bobrov, Alexander G., Weaver, Robert H., DeMoll, Edward, Perry, Robert D.
Formato:	Texto
Lenguaje:	English
Publicado:	Microbiology Society 2010
Materias:	Microbial Pathogenicity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068685/ https://www.ncbi.nlm.nih.gov/pubmed/20413552 http://dx.doi.org/10.1099/mic.0.037945-0

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