Cargando…

Double suicide genes driven by kinase domain insert containing receptor promoter selectively kill human lung cancer cells

BACKGROUND: To investigate the selective killing efficacy of the double suicide genes driven by KDR promoter. MATERIALS AND METHODS: A double suicide gene system with the KDR promoter, pcDNA3-KDRp-CDglyTK, was constructed and transfected into lung cancer cell lines L9981 and NL9980, and human hepato...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Junrong, Li, Mi, Mei, Longyong, Zhou, Qinghua, Liu, Lunxu, Yu, Xijie, Che, Guowei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068930/ https://www.ncbi.nlm.nih.gov/pubmed/21418659 http://dx.doi.org/10.1186/1479-0556-9-6

Ejemplares similares

Double suicide genes selectively kill human umbilical vein endothelial cells
por: Jia, Weiguo, et al.
Publicado: (2011)

A novel differential diagnostic model for multiple primary lung cancer: Differentially-expressed gene analysis of multiple primary lung cancer and intrapulmonary metastasis
por: CHEN, DALI, et al.
Publicado: (2015)

Association of kinase insert domain-containing receptor (KDR) gene polymorphism/ haplotypes with recurrent spontaneous abortion and genetic structure
por: Shahsavari, Shiva, et al.
Publicado: (2015)

Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation
por: Bullock, Alex N., et al.
Publicado: (2009)

Amino substituted nitrogen heterocycle ureas as kinase insert domain containing receptor (KDR) inhibitors: Performance of structure–activity relationship approaches
por: Yilmaz, Hayriye, et al.
Publicado: (2015)

Conservation of land plant-specific receptor-like cytoplasmic kinase subfamily XI possessing a unique kinase insert domain
por: Yayen, Joseph, et al.
Publicado: (2023)

From autothanasia to suicide: self-killing in classical antiquity
por: Nutton, Vivian
Publicado: (1991)

In the Multi-domain Protein Adenylate Kinase, Domain Insertion Facilitates Cooperative Folding while Accommodating Function at Domain Interfaces
por: Giri Rao, V. V. Hemanth, et al.
Publicado: (2014)

Association of Kinase-Insert-Domain-Containing Receptor Polymorphisms with Glioma Susceptibility in a Chinese Population: A Hospital-Based Case-Control Study
por: Huang, Zhi-Fa, et al.
Publicado: (2023)

Cavernous hemangioma of thymus misdiagnosed as thymoma: a case report
por: Shen, Cheng, et al.
Publicado: (2014)

Reversibly immortalized hepatic progenitor cell line containing double suicide genes
por: Fang, Shu-Yu, et al.
Publicado: (2018)

Does Generic Cyclic Kinase Insert Domain of Receptor Tyrosine Kinase KIT Clone Its Native Homologue?
por: Ledoux, Julie, et al.
Publicado: (2022)

The -271 G>A polymorphism of kinase insert domain-containing receptor gene regulates its transcription level in patients with non-small cell lung cancer
por: An, She-Juan, et al.
Publicado: (2009)

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
por: Ma, Junliang, et al.
Publicado: (2010)

The Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis Offers Efficient Bystander Cell Killing for Suicide Gene Therapy of Cancer
por: Sato, Takeya, et al.
Publicado: (2013)

Targeted insertional mutagenesis libraries for deep domain insertion profiling
por: Coyote-Maestas, Willow, et al.
Publicado: (2020)

Targeted insertional mutagenesis libraries for deep domain insertion profiling
por: Coyote-Maestas, Willow, et al.
Publicado: (2020)

Ankyrin Repeat and Kinase Domain Containing 1 Gene, and Addiction Vulnerability
por: Koeneke, Alejandra, et al.
Publicado: (2020)

“Deadman” and “Passcode” microbial kill switches for bacterial containment
por: Chan, Clement T. Y., et al.
Publicado: (2015)

Black Mn-containing layered double hydroxide coated magnesium alloy for osteosarcoma therapy, bacteria killing, and bone regeneration
por: Zhang, Dongdong, et al.
Publicado: (2022)

The unstructured domain of colicin N kills Escherichia coli
por: Johnson, Christopher L, et al.
Publicado: (2013)

Whole-chromosome hitchhiking driven by a male-killing endosymbiont
por: Martin, Simon H., et al.
Publicado: (2020)

Selective enhancement of hypoxic cell killing by tempol-regulated suicide gene expression
por: KAGIYA, GO, et al.
Publicado: (2015)

Folding and Intrinsic Disorder of the Receptor Tyrosine Kinase KIT Insert Domain Seen by Conventional Molecular Dynamics Simulations
por: Ledoux, Julie, et al.
Publicado: (2021)

An optogenetic toolbox of LOV-based photosensitizers for light-driven killing of bacteria
por: Endres, Stephan, et al.
Publicado: (2018)

Lung Adenocarcinoma Harboring EGFR Kinase Domain Duplication (EGFR-KDD) Confers Sensitivity to Osimertinib and Nivolumab: A Case Report
por: Li, Jie, et al.
Publicado: (2020)

“Unique trend” and “contradictory trend” in discrimination of primary synchronous lung cancer and metastatic lung cancer
por: Shen, Cheng, et al.
Publicado: (2013)

Prognostic value of TGF-β in lung cancer: systematic review and meta-analysis
por: Li, Jue, et al.
Publicado: (2019)

Autoimmunity as a Double Agent in Tumor Killing and Cancer Promotion
por: Toomer, Kevin H., et al.
Publicado: (2014)

Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas
por: Xie, Weiyan, et al.
Publicado: (2016)

Domain-Driven Laravel: Learn to Implement Domain-Driven Design Using Laravel
por: Griffin, Jesse
Publicado: (2020)

Trypanosoma brucei Mitochondrial DNA Polymerase POLIB Contains a Novel Polymerase Domain Insertion That Confers Dominant Exonuclease Activity
por: Delzell, Stephanie B., et al.
Publicado: (2022)

Caspase-independent Cell Killing by Fas-associated Protein with Death Domain
por: Kawahara, Atsuo, et al.
Publicado: (1998)

Percutaneous insertion of bilateral double J stent
por: Nunes, Thiago Franchi, et al.
Publicado: (2019)

Double lumen tube: Size and insertion depth
por: Eldawlatly, Abdelazeem A.
Publicado: (2021)

Putting Suicide Policy through the Wringer: Perspectives of Military Members Who Attempted to Kill Themselves
por: LeFeber, Tirzah Parrish, et al.
Publicado: (2019)

Suicide and Neurotrophin Factors: A Systematic Review of the Correlation between BDNF and GDNF and Self-Killing
por: De Simone, Stefania, et al.
Publicado: (2022)

Oriented Insertion of ESR-Containing Hybrid Proteins in Proteoliposomes
por: Petrovskaya, Lada E., et al.
Publicado: (2023)

Consecutive and Selective Double Methylene Insertion of Lithium Carbenoids to Isothiocyanates: A Direct Assembly of Four‐Membered Sulfur‐Containing Cycles
por: Senatore, Raffaele, et al.
Publicado: (2021)

The NTPase activity of the double FYVE domain–containing protein 1 regulates lipid droplet metabolism
por: Ismail, V.A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5fg0sncnkt1iimrjkmq01kghcq