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Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells

BACKGROUND: Autotaxin (ATX) possesses lysophospholipase D (lyso PLD) activity, which converts lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA). The ATX-LPA signaling axis has been implicated in angiogenesis, chronic inflammation and tumor progression. Osteopontin (OPN) is an important...

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Detalles Bibliográficos
Autores principales:	Zhang, Rihua, Wang, Jing, Ma, Shijie, Huang, Zuhu, Zhang, Guoxin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068946/ https://www.ncbi.nlm.nih.gov/pubmed/21406114 http://dx.doi.org/10.1186/1471-2121-12-11

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