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Lung Adenocarcinoma Originates from Retrovirus Infection of Proliferating Type 2 Pneumocytes during Pulmonary Post-Natal Development or Tissue Repair

Jaagsiekte sheep retrovirus (JSRV) is a unique oncogenic virus with distinctive biological properties. JSRV is the only virus causing a naturally occurring lung cancer (ovine pulmonary adenocarcinoma, OPA) and possessing a major structural protein that functions as a dominant oncoprotein. Lung cance...

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Detalles Bibliográficos
Autores principales: Murgia, Claudio, Caporale, Marco, Ceesay, Ousman, Di Francesco, Gabriella, Ferri, Nicola, Varasano, Vincenzo, de las Heras, Marcelo, Palmarini, Massimo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068994/
https://www.ncbi.nlm.nih.gov/pubmed/21483485
http://dx.doi.org/10.1371/journal.ppat.1002014