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RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo

The integrity of the retinoblastoma tumor suppressor (RB) pathway is critical for restraining inappropriate proliferation and suppressing tumor development in a plethora of tissues. Here adenovirus-mediated RB deletion in the liver of adult mice led to DNA replication in the absence of productive mi...

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Detalles Bibliográficos
Autores principales:	Bourgo, Ryan J., Ehmer, Ursula, Sage, Julien, Knudsen, Erik S.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069018/ https://www.ncbi.nlm.nih.gov/pubmed/21289097 http://dx.doi.org/10.1091/mbc.E10-11-0895

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