Cargando…

RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo

The integrity of the retinoblastoma tumor suppressor (RB) pathway is critical for restraining inappropriate proliferation and suppressing tumor development in a plethora of tissues. Here adenovirus-mediated RB deletion in the liver of adult mice led to DNA replication in the absence of productive mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bourgo, Ryan J., Ehmer, Ursula, Sage, Julien, Knudsen, Erik S.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069018/ https://www.ncbi.nlm.nih.gov/pubmed/21289097 http://dx.doi.org/10.1091/mbc.E10-11-0895

Ejemplares similares

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
por: Viatour, Patrick, et al.
Publicado: (2011)

Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
por: Kruitwagen, Tom, et al.
Publicado: (2018)

DNA replication and mitotic entry: A brake model for cell cycle progression
por: Lemmens, Bennie, et al.
Publicado: (2019)

Ongoing replication forks delay the nuclear envelope breakdown upon mitotic entry
por: Hashimoto, Yoshitami, et al.
Publicado: (2020)

Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth
por: Li, Juan, et al.
Publicado: (2017)

Mitotic UV Irradiation Induces a DNA Replication-Licensing Defect that Potentiates G1 Arrest Response
por: Morino, Masayuki, et al.
Publicado: (2015)

Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe
por: Gastl, Bastian, et al.
Publicado: (2020)

Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination
por: Bourgo, Ryan J., et al.
Publicado: (2016)

The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation
por: Volpi, Ilaria, et al.
Publicado: (2021)

Newly identified aspects of tumor suppression by RB
por: Viatour, Patrick, et al.
Publicado: (2011)

ELYS/MEL-28 Chromatin Association Coordinates Nuclear Pore Complex Assembly and Replication Licensing
por: Gillespie, Peter J., et al.
Publicado: (2007)

Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe
por: Kuenzel, Natascha Andrea, et al.
Publicado: (2022)

p107 in the public eye: an Rb understudy and more
por: Wirt, Stacey E, et al.
Publicado: (2010)

Rb and chromatin remodeling in the maintenance of the post-mitotic state of neurons
por: Blais, Alexandre
Publicado: (2013)

Regulation of DNA Replication Licensing and Re-Replication by Cdt1
por: Zhang, Hui
Publicado: (2021)

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry()
por: Lee, Kyung-Jong, et al.
Publicado: (2015)

Transcriptional control of DNA replication licensing by Myc
por: Valovka, Taras, et al.
Publicado: (2013)

Mitotic entry elucidated with bacterial toxin toolbox
por: Barth, Holger, et al.
Publicado: (2014)

Nucleus-Cytoskeleton Crosstalk During Mitotic Entry
por: Dantas, Margarida, et al.
Publicado: (2021)

Differential role of RB in response to UV and IR damage
por: Bosco, Emily E., et al.
Publicado: (2005)

Non-canonical pathway for Rb inactivation and external signaling coordinate cell-cycle entry without CDK4/6 activity
por: Zhang, Mimi, et al.
Publicado: (2023)

MASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activation
por: Wong, Po Yee, et al.
Publicado: (2016)

The dynamics of replication licensing in live Caenorhabditis elegans embryos
por: Sonneville, Remi, et al.
Publicado: (2012)

DNA replication origins retain mobile licensing proteins
por: Sánchez, Humberto, et al.
Publicado: (2021)

Redundant Mechanisms Prevent Mitotic Entry Following Replication Arrest in the Absence of Cdc25 Hyper-Phosphorylation in Fission Yeast
por: Frazer, Corey, et al.
Publicado: (2011)

Robust mitotic entry is ensured by a latching switch
por: Tuck, Chloe, et al.
Publicado: (2013)

Rapid DNA replication origin licensing protects stem cell pluripotency
por: Matson, Jacob Peter, et al.
Publicado: (2017)

CDC7 kinase (DDK) inhibition disrupts DNA replication leading to mitotic catastrophe in Ewing sarcoma
por: Martin, Jeffrey C., et al.
Publicado: (2022)

Subtypes of oligodendroglioma defined by 1p,19q deletions, differ in the proportion of apoptotic cells but not in replication-licensed non-proliferating cells
por: Wharton, S. B., et al.
Publicado: (2006)

RB depletion is required for the continuous growth of tumors initiated by loss of RB
por: Doan, Alex, et al.
Publicado: (2021)

Defining a new vision for the retinoblastoma gene: report from the 3rd International Rb Meeting
por: Rubin, Seth M, et al.
Publicado: (2013)

Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry
por: Fasulo, Barbara, et al.
Publicado: (2012)

DNA replication licensing and cell cycle kinetics of oligodendroglial tumours
por: Wharton, S B, et al.
Publicado: (2004)

Functional domains of the Xenopus replication licensing factor Cdt1
por: Ferenbach, Andrew, et al.
Publicado: (2005)

ATPase-Dependent Quality Control of DNA Replication Origin Licensing
por: Frigola, Jordi, et al.
Publicado: (2013)

Cryo-EM structure of a licensed DNA replication origin
por: Abid Ali, Ferdos, et al.
Publicado: (2017)

DNA Replication Licensing Proteins for Early Detection of Lung Cancer
por: VS, Veena, et al.
Publicado: (2017)

DNA replication licensing in stem cells: Gatekeeping the commitment to proliferation
por: Coller, Hilary A.
Publicado: (2018)

Dynamic assembly of Hda and the sliding clamp in the regulation of replication licensing
por: Kim, Jin S., et al.
Publicado: (2017)

Cellular cholesterol licenses Legionella pneumophila intracellular replication in macrophages
por: Ondari, Edna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_oclfsgfki6536ph5r6ufedctg4