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DDR1 triggers epithelial cell differentiation by promoting cell adhesion through stabilization of E-cadherin

Discoidin domain receptor 1 (DDR1) promotes E-cadherin–mediated adhesion. The underlying mechanism and its significance, however, have not been elucidated. Here we show that DDR1 overexpression augmented, whereas dominant negative mutant (DN-DDR1) or knockdown of DDR1 inhibited E-cadherin localized...

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Detalles Bibliográficos
Autores principales: Yeh, Yi-Chun, Wu, Chia-Ching, Wang, Yang-Kao, Tang, Ming-Jer
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069019/
https://www.ncbi.nlm.nih.gov/pubmed/21289093
http://dx.doi.org/10.1091/mbc.E10-08-0678