Cargando…
Structuring Detergents for Extracting and Stabilizing Functional Membrane Proteins
BACKGROUND: Membrane proteins are privileged pharmaceutical targets for which the development of structure-based drug design is challenging. One underlying reason is the fact that detergents do not stabilize membrane domains as efficiently as natural lipids in membranes, often leading to a partial t...
Autores principales: | Matar-Merheb, Rima, Rhimi, Moez, Leydier, Antoine, Huché, Frédéric, Galián, Carmen, Desuzinges-Mandon, Elodie, Ficheux, Damien, Flot, David, Aghajari, Nushin, Kahn, Richard, Di Pietro, Attilio, Jault, Jean-Michel, Coleman, Anthony W., Falson, Pierre |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069034/ https://www.ncbi.nlm.nih.gov/pubmed/21483854 http://dx.doi.org/10.1371/journal.pone.0018036 |
Ejemplares similares
-
Diffraction anisotropy falloff in the direction of the detergent belt for two centered monoclinic crystals of OmpF
por: Chaptal, Vincent, et al.
Publicado: (2016) -
Structural and Functional Characterization of Drosophila melanogaster α-Amylase
por: Rhimi, Moez, et al.
Publicado: (2023) -
The acid-tolerant L-arabinose isomerase from the mesophilic Shewanella sp. ANA-3 is highly active at low temperatures
por: Rhimi, Moez, et al.
Publicado: (2011) -
Stubborn Contaminants: Influence of Detergents on the Purity of the Multidrug ABC Transporter BmrA
por: Wiseman, Benjamin, et al.
Publicado: (2014) -
Quantification of Detergents Complexed with Membrane Proteins
por: Chaptal, Vincent, et al.
Publicado: (2017)