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Application of Silicon Photomultipliers to Positron Emission Tomography

Historically, positron emission tomography (PET) systems have been based on scintillation crystals coupled to photomultipliers tubes (PMTs). However, the limited quantum efficiency, bulkiness, and relatively high cost per unit surface area of PMTs, along with the growth of new applications for PET,...

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Detalles Bibliográficos
Autores principales: Roncali, Emilie, Cherry, Simon R.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069330/
https://www.ncbi.nlm.nih.gov/pubmed/21321792
http://dx.doi.org/10.1007/s10439-011-0266-9
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author Roncali, Emilie
Cherry, Simon R.
author_facet Roncali, Emilie
Cherry, Simon R.
author_sort Roncali, Emilie
collection PubMed
description Historically, positron emission tomography (PET) systems have been based on scintillation crystals coupled to photomultipliers tubes (PMTs). However, the limited quantum efficiency, bulkiness, and relatively high cost per unit surface area of PMTs, along with the growth of new applications for PET, offers opportunities for other photodetectors. Among these, small-animal scanners, hybrid PET/MRI systems, and incorporation of time-of-flight information are of particular interest and require low-cost, compact, fast, and magnetic field compatible photodetectors. With high quantum efficiency and compact structure, avalanche photodiodes (APDs) overcome several of the drawbacks of PMTs, but this is offset by degraded signal-to-noise and timing properties. Silicon photomultipliers (SiPMs) offer an alternative solution, combining many of the advantages of PMTs and APDs. They have high gain, excellent timing properties and are insensitive to magnetic fields. At the present time, SiPM technology is rapidly developing and therefore an investigation into optimal design and operating conditions is underway together with detailed characterization of SiPM-based PET detectors. Published data are extremely promising and show good energy and timing resolution, as well as the ability to decode small scintillator arrays. SiPMs clearly have the potential to be the photodetector of choice for some, or even perhaps most, PET systems.
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spelling pubmed-30693302011-05-02 Application of Silicon Photomultipliers to Positron Emission Tomography Roncali, Emilie Cherry, Simon R. Ann Biomed Eng Article Historically, positron emission tomography (PET) systems have been based on scintillation crystals coupled to photomultipliers tubes (PMTs). However, the limited quantum efficiency, bulkiness, and relatively high cost per unit surface area of PMTs, along with the growth of new applications for PET, offers opportunities for other photodetectors. Among these, small-animal scanners, hybrid PET/MRI systems, and incorporation of time-of-flight information are of particular interest and require low-cost, compact, fast, and magnetic field compatible photodetectors. With high quantum efficiency and compact structure, avalanche photodiodes (APDs) overcome several of the drawbacks of PMTs, but this is offset by degraded signal-to-noise and timing properties. Silicon photomultipliers (SiPMs) offer an alternative solution, combining many of the advantages of PMTs and APDs. They have high gain, excellent timing properties and are insensitive to magnetic fields. At the present time, SiPM technology is rapidly developing and therefore an investigation into optimal design and operating conditions is underway together with detailed characterization of SiPM-based PET detectors. Published data are extremely promising and show good energy and timing resolution, as well as the ability to decode small scintillator arrays. SiPMs clearly have the potential to be the photodetector of choice for some, or even perhaps most, PET systems. Springer US 2011-02-15 2011 /pmc/articles/PMC3069330/ /pubmed/21321792 http://dx.doi.org/10.1007/s10439-011-0266-9 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Roncali, Emilie
Cherry, Simon R.
Application of Silicon Photomultipliers to Positron Emission Tomography
title Application of Silicon Photomultipliers to Positron Emission Tomography
title_full Application of Silicon Photomultipliers to Positron Emission Tomography
title_fullStr Application of Silicon Photomultipliers to Positron Emission Tomography
title_full_unstemmed Application of Silicon Photomultipliers to Positron Emission Tomography
title_short Application of Silicon Photomultipliers to Positron Emission Tomography
title_sort application of silicon photomultipliers to positron emission tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069330/
https://www.ncbi.nlm.nih.gov/pubmed/21321792
http://dx.doi.org/10.1007/s10439-011-0266-9
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